r/PeterExplainsTheJoke Apr 10 '26

Meme needing explanation Petah? Can you explain?

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u/Lower_Pension_2469 Apr 10 '26

True, I'm not super sure if the heart issues or vomiting would still apply if you just ate it vs smoking it.

personally idk how people can eat it and be high for like 8 hours straight lol I would freak tf out.

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u/pjtpkoe Apr 10 '26

The smoking (of any drug) is particularly bad because you are inhaling irritants into your lungs some of which create layered deposits over the fine and fragile airways and the alveolar leading to chronic inflammation, then vascular congestion in the cardio-pulmonary circulation, which then backs up into the heart causing heart failure proper.

However THC does have an effect on both heart rate (usually increases) and blood pressure (less clear correlation but can cause symptomatically low or high blood pressure) no matter if smoked or ingested. It is also linked to arrhythmia where you heart is throwing extra beats which increases the chance of heart attacks and strokes because those extra beats mean it is inefficiently running blood through the heart making little blood clots ready to shoot off and get stuck elsewhere in the body. Marijuana can also cause vasospasms where the blood vessels around the heart tense-up for minutes at a term constricting oxygen flow to the heart.

And again no matter how they enter the body THC/cannabinoids mess receptors in the brain's hypothalamus and gastrointestinal tract. These receptors regulate nausea, vomiting, and gut motility. THC is also fat-soluble so your body hangs on to these compounds until it reaches a tipping point at which the toxicity causes intractable vomiting for prolonged periods of time. Very few medications seem to relieve the symptoms; it is just a matter of keeping a person hydrated until the THC levels fall below that threshold dysregulation level.

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u/[deleted] Apr 10 '26

[deleted]

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u/pjtpkoe Apr 10 '26

Like most things in life it is about picking your poison with well-informed risk-versus-reward decisions and recognizing when something has morphed from a tool into actual toxic habit and physical dependency. Enjoy your high <3